METABOLOMICS

METABOLOMICS

The Laura and Isaac Perlmutter Metabolomics & Lipidomics Center

The Laura and Isaac Perlmutter Metabolomics & Lipidomics Center was established through a generous donation from the Laura and Isaac Perlmutter Foundation. The Foundation is dedicated to improving the lives of others – with a particular focus on health care, social justice, the arts and community initiatives.

Why metabolomics?

Metabolites are the end products of cellular activity, so they offer the most direct readout of what is happening in a cell, tissue or organism at a given moment. Measuring them, together with lipids and energy metabolism, connects genes and proteins to function, reveals disease mechanisms and drug effects, and helps identify biomarkers.

The center supports metabolism-focused research across the Technion, as well as academic institutions, hospitals and industry throughout Israel. We measure small molecules and lipids in cells, tissues and biological fluids, and assess energy metabolism in living cells, using state-of-the-art LC-MS and GC-MS platforms and the Seahorse Real-Time Cell Metabolic Analyzer.

We offer a broad range of targeted and untargeted assays, together with method development for new compounds. Our team works closely with every researcher, from planning the experiment to interpreting the results.

VIDEO · 0:32
The facility at a glance
Meet our team, our instruments and what we measure, in under a minute.

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Metabolism, from every angle

Our platforms interlock to give a comprehensive view of metabolism: the small molecules, the lipids, and the energy that keeps cells running, each with a broad range of dedicated assays.

MetabolomicsLipidomicsEnergy
1

Metabolomics
Small molecules: sugars, amino acids, nucleotides and more, targeted or untargeted, by LC-MS and GC-MS.
2

Lipidomics
The lipids that build membranes and store and signal energy: more than 25 lipid classes, plus fatty acids.
3

Live-cell energy metabolism
How living cells run, in real time: respiration, glycolysis and ATP production on the Seahorse.

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We work with you, from question to insight

Every project is a collaboration. We help you design the experiment, run the samples and the analysis, and think through the results together with you.

Kick-off meeting
Pilotwhen needed
Sample prep
& measurement
Data analysis
Insights, together
Your question, our expertise: we design the experiment together.
A small test run to make sure the method fits your samples.
LC-MS, GC-MS or Seahorse, matched to your question.
Processing, statistics and annotation of your results.
We go over the results together and think about what comes next.
New questions often lead to the next experiment.
Sample types:CellsTissuesBloodUrineSalivaCSFand more
Planning a metabolomics experiment?
Contact us to consult on a new project.
Ifat Abramovich, MSc
Head of the Perlmutter Metabolomics & Lipidomics Center

ifat.a@technion.ac.il+972 73 378 5468

Technologies
Technologies
Applications
Applications
Data Analysis
Data Analysis
Contact Us
Contact Us